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. 2021 Dec 17;8:738378. doi: 10.3389/fcvm.2021.738378

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Copyright © 2021 Wang, Cao, Ji, Li, Xue, Li, Jia and Ding.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of different concentrations of AEDPPE on HTR-8/SVneo cell function. (A) AEDPPE had no significant effect on the proliferation of HTR-8/SVneo cells. (B) Different concentrations of AEDPPE did not affect apoptosis of HTR-8/SVneo cells. (C) The effects of various concentrations of AEDPPE on the expression levels of IL-1β, IL-6, and IL-8 mRNA and the protein content of IL-6 in the cellular supernatant. (D) Wound healing was significantly enhanced by AEDPPE treatment of HTR-8/SVneo cells (scale bar = 400 μm). (E) AEDPPE promoted the migration and invasion of HTR-8/SVneo cells (scale bar = 200 μm). *p < 0.05, **p < 0.01, ***p < 0.001 vs. the control group.