Table 2.
List of 25 most significant sequenced peptides of IgAN237 with lowest adjusted P-values
| Peptide ID | Corr. P-value | Mean amplitude progressors (training) | Mean amplitude non-progressors (training) | Fold change | Sequence | Protein name | Protein symbol | Start AA | Stop AA |
|---|---|---|---|---|---|---|---|---|---|
| 99915883 | 0.0105 | 8.96 | 58.32 | 0.154 | NSGEpGApGSK GDTGAKGEp GPVGVQGPpGPAG | Collagen alpha-1(I) chain | COL1A1 | 432 | 464 |
| 99910985 | 0.0105 | 43.83 | 86.99 | 0.504 | NSGEKGDQGFQ GQPGFPGPPGP | Collagen alpha- 1(XVI) chain | COL16A1 | 1145 | 1166 |
| 99907573 | 0.0105 | 92.15 | 292.94 | 0.315 | ESVVLEPEAT | Fractalkine | X3CL1 | 123 | 132 |
| 99910668 | 0.0123 | 1497.39 | 2131.3 | 0.703 | GpPGEAGKpGEQ GVpGDLGAPGp | Collagen alpha- 1(I) chain | COL1A1 | 650 | 672 |
| 99914456 | 0.0123 | 28.16 | 450.67 | 0.062 | DLQVGQVELGGGPGA GSLQPLALEGSLQ | Insulin | INS | 60 | 87 |
| 99904786 | 0.0125 | 69.59 | 122.18 | 0.570 | SpGSPGPDGKTGPPGP | Collagen alpha- 1(I) chain | COL1A1 | 543 | 559 |
| 99917505 | 0.0157 | 122.02 | 283.96 | 0.430 | AGRpGEVGPpGPpGPAGEKG SPGADGPAGAPGTpGPQG | Collagen alpha-1 (I) chain | COL1A1 | 916 | 953 |
| 99917388 | 0.0157 | 99.88 | 204.59 | 0.488 | GPpGppGRDGEDGPTGP pGPPGPPGPPGLGGNFAAQ | Collagen alpha-2(I) chain | COL1A2 | 45 | 80 |
| 99916194 | 0.0167 | 26.62 | 623.15 | 0.043 | EAEDLQVGQVELGGG PGAGSLQPLALEGSLQ | Insulin | INS | 57 | 87 |
| 99910573 | 0.0168 | 987.11 | 1499.34 | 0.658 | GPpGEAGKpGEQ GVpGDLGAPGP | Collagen alpha-1(I) chain | COL1A1 | 650 | 672 |
| 99912693 | 0.0175 | 31.22 | 51.49 | 0.606 | GPAGpPGKAGEDGH PGKpGRpGERG | Collagen alpha-2(I) chain | COL1A2 | 133 | 157 |
| 99908185 | 0.0179 | 108.3 | 412.91 | 0.262 | EEAPSLRPAPPPISGGGY | Fibrinogen beta chain | FGB | 54 | 71 |
| 99914501 | 0.0179 | 98.36 | 152.89 | 0.643 | pPGADGQPGAKGEpGD AGAKGDAGpPGPAGP | Collagen alpha-1(I) chain | COL1A1 | 816 | 846 |
| 99909057 | 0.0186 | 3.49 | 35.74 | 0.098 | GpAGATGDRGEAG AAGPAGpAGP | Collagen alpha-2(I) chain | COL1A2 | 685 | 707 |
| 99903148 | 0.0234 | 1279.9 | 275.75 | 4.642 | FMGKVVNPTQK | Alpha-1-antitrypsin | SERPINA1 | 408 | 418 |
| 99910838 | 0.0234 | 25.77 | 61.51 | 0.419 | GpTGpIGPpGpAGQ PGDKGEGGAP | Collagen alpha-1(III) chain | COL3A1 | 762 | 785 |
| 99908885 | 0.0240 | 3223.72 | 6243.43 | 0.516 | AAHLPAEFTPAVHASLDK | Haemoglobin subunit alpha | HBA1 | 111 | 128 |
| 99917047 | 0.0242 | 2828.47 | 4810.36 | 0.588 | PpGESGREGApGAEGSp GRDGSpGAKGDRGETGP | Collagen alpha-1(I) chain | COL1A1 | 1008 | 1041 |
| 99906068 | 0.0242 | 326.45 | 545.87 | 0.598 | NDGApGKNGERGGpGGP | Collagen alpha-1(III) chain | COL3A1 | 586 | 602 |
| 99909564 | 0.0242 | 18.51 | 96.54 | 0.192 | GEKGpSGEAGTA GPpGTpGPQG | Collagen alpha-2(I) chain | COL1A2 | 844 | 865 |
| 99913909 | 0.0242 | 902.04 | 5019.41 | 0.180 | EKSAVTALWGKVNV DEVGGEALGRL | Haemoglobin subunit beta | HBB | 8 | 32 |
| 99906402 | 0.0254 | 11.3 | 57.83 | 0.195 | WQGVEVGEAGQGKDF | Basement membrane- specific heparan sulfate proteoglycan core protein | HSPG2 | 4245 | 4259 |
| 99912198 | 0.0254 | 134.56 | 344.73 | 0.390 | AGppGEAGKPGEQGV pGDLGApGPSG | Collagen alpha-1(I) chain | COL1A1 | 649 | 674 |
| 99913650 | 0.0266 | 20.96 | 63.72 | 0.329 | GpTGATGDKGPPG PVGPPGSNGpVGEpGP | Collagen alpha-2(V) chain | COL5A2 | 1020 | 1048 |
| 99905463 | 0.0276 | 60.81 | 258.26 | 0.235 | ApGDKGESGPSGPAGPT | Collagen alpha-1(I) chain | COL1A1 | 777 | 793 |