Table 1.
Characteristics of Study Population and Episodes of Moderate-to-Severe Diarrhea
| Child-Level Characteristics | All Children Included in Etiology Sub-studya | ||
|---|---|---|---|
| Number of children | 4128 | ||
| Male sex | 2029 (49.2) | ||
| Enrollment weight (kg) | 54.3 ± 2.5 | ||
| Enrollment length (cm) | 4.5 ± 0.7 | ||
| Randomized to Rotasiil arm | 2096 (50.8) | ||
| Mother completed primary school | 271 (6.6) | ||
| Mother can read | 1190 (28.9) | ||
| Number of children under 5 in home | 2.7 ± 1.3 | ||
| No water treatment in home | 3753 (90.9) | ||
| Unimproved floor in home | 2427 (59.0) | ||
| Unimproved drinking water source | 397 (9.7) | ||
| Unimproved latrine | 1908 (46.4) | ||
| Episode-Level Characteristics | All Episodes | Episodes With Valid TAC Result (Unweighted) | Episodes With Valid TAC Result (Weighted) |
| Number of episodes of moderate/severe diarrhea | 3344 | 1715 | N/A |
| Age (wk) | 42.5 ± 23.7 | 49.9 ± 27.8 | 42.6 ± 23.6 |
| Age 0-5 mo | 823 (24.6) | 454 (26.4) | 422 (24.6) |
| Age 6-11 mo | 1587 (47.5) | 451 (26.3) | 815 (47.4) |
| Age 12-17 mo | 547 (16.4) | 446 (26.0) | 281 (16.3) |
| Age 18-23 m | 387 (11.6) | 366 (21.3) | 200 (11.7) |
| Vesikari score | 9.5 ± 2.5 | 9.3 ± 2.4 | 9.5 ± 2.5 |
| Severe (Vesikari >= 11?) | 1002 (30.0) | 459 (26.7) | 517 (30.1) |
| Duration of diarrhea (d) | 3.8 ± 2.3 | 3.7 ± 2.2 | 3.8 ± 2.3 |
| Maximum loose stools in 24 h | 4.8 ± 1.3 | 4.7 ± 1.2 | 4.8 ± 1.3 |
| Vomiting | 1386 (41.4) | 638 (37.2) | 703 (41.0) |
| Duration of vomiting (days) | 2.1 ± 1.6 | 2 ± 1.6 | 2.1 ± 1.6 |
| Maximum vomiting episodes in 24 h | 2.2 ± 1.5 | 2.2 ± 1.4 | 2.2 ± 1.4 |
| Objective fever (>= 38.0°C) | 620 (18.5) | 325 (18.9) | 331 (19.3) |
| Severe dehydration | 49 (1.5) | 27 (1.6) | 31 (1.8) |
| Some dehydration | 238 (7.1) | 110 (6.4) | 128 (7.4) |
| No dehydration | 3057 (91.4) | 1580 (92.0) | 1558 (90.7) |
| Hospitalized | 277 (8.6) | 127 (7.7) | 139 (8.4) |
Abbreviation: TAC, TaqMan Array Card.
aData shown are N (%) for dichotomous variables and mean ± standard deviation for continuous variables.