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. 2021 Dec 15;27(3):697–704. doi: 10.1016/j.drudis.2021.12.010

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© 2021 The Authors

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Pfizer’s new molecular entities (NMEs) versus product extensions (PE) success rates for Phase II, Phase III, and Approval from 2016 to 2020. Success rates are defined as in Fig. 1, for NME and PE cohorts separately. N is the total number of NME or PE programs for that stage within the time period analyzed. These were calculated using 5-year rolling averages. Data from Pfizer pipeline analysis.