Table 1. The hemodynamic parameters in TNF-α–challenged WT and DREAM KO mice.

Genotype	WBC (cells/μl)	% of neutrophils	Diameter of venules (μm)	Blood flow rate (μl−6/s)
WT	3,100 ± 750	39 ± 6	33.5 ± 4	426 ± 105
DREAM KO	4,300 ± 1,220	45 ± 9	35.2 ± 4	652 ± 129*

Mice were treated with intrascrotal injection of TNF-α, followed by intravital microscopy as described in Fig. 1. After 1 h imaging, fluorescently labeled microspheres (diameter: 200 nm) were injected into mice, and the centerline velocity was calculated to assess blood flow rates. Data represent the mean ± SD (n = 12 venules in 6 mice per group). *, P < 0.05 versus WT mice after Student’s t test. WBC, white blood cells.