Table 2. The hemodynamic parameters in TNF-α–challenged DREAM BM chimeric mice.
Mice | WBC (cells/µl) | % of neutrophils | Diameter of venules (μm) | Blood flow rate (μl−6/s) |
---|---|---|---|---|
WT-BM → WT | 2,800 ± 660 | 37 ± 7 | 33.5 ± 4 | 456 ± 102 |
WT-BM → KO | 3,400 ± 950 | 44 ± 8 | 35.1 ± 4 | 582 ± 129 |
KO-BM → WT | 3,700 ± 1,120 | 45 ± 8 | 33.1 ± 3 | 605 ± 145 |
KO-BM → KO | 3,600 ± 1,190 | 45 ± 9 | 36.2 ± 4 | 725 ± 153* |
All parameters were measured as described in Table 1. Data represent the mean ± SD (n = 6 mice per group). *, P < 0.05 versus WT-BM → WT mice after ANOVA and Dunnett’s test. WBC, white blood cells.