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. 2021 Dec 17;11:650980. doi: 10.3389/fonc.2021.650980

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Copyright © 2021 Yin, Zhang, Li, Zhang, Liu and Yuan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nomogram for the prediction of DFS. (A) A nomogram for predicting the 5-year DFS for 440 patients with breast cancer (molecular subtype: 1 = luminal A, 2 = luminal B, 3 = HER-2, 4 = TNBC). To calculate the 5-year DFS for a specific patient, locate patient’s pretreatment LMR and draw a line straight upward to the Points axis to determine the score associated to that LMR. Repeat the process for TNM stage and molecular subtype, sum the scores, and locate this sum on the Total Points axis. Then, draw a line straight down to the corresponding “5-year DFS” axis to find the predicted 5-year DFS. (B) Calibration curves for 5-year DFS using nomograms with TNM stage, molecular subtype, and pretreatment LMR are shown. The x-axis is nomogram predicted probability of survival and y-axis is actual survival. The bootstrapping method was used for the internal validation of the nomogram. The gray line indicates perfect calibration.