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. 2021 Dec 31;16(12):e0256885. doi: 10.1371/journal.pone.0256885

Fig 2. Vaccine-induced Env binding IgG responses against HIV 1086c gp120 K160N does not correlate with frequency of antigen-specific memory B cells in infants.

Fig 2

(A) Binding antibody level was significantly higher in the 3M-052-SE group as measured by ELISA at peak immunogenicity. (B) Binding antibody levels at peak immunogenicity was not correlated with antigen-specific memory B cell frequencies in all vaccine groups. Statistical analyses were performed with GraphPad Prism, * denoted significant p-values of <0.05 by a non-parametric Mann-Whitney test. Correlation analysis was performed using Spearman’s rank correlation test with GraphPad Prism, with p-value of <0.05 considered as significant.