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. 2021 Dec 31;16(12):e0257972. doi: 10.1371/journal.pone.0257972

Fig 12. PD-1 receptor occupancy and PK profiles.

Fig 12

(a) Mean Serum drug concentration-time curves of HLX10 following a single IV-infusion at 3, 10 and 30 mg/kg (N = 3). (b) Receptor occupancy rate of HLX10 on PD-1 on the surface of T cells following a single IV-infusion at 3, 10 and 30 mg/kg, which was assessed by flow cytometry.