Table 1. Kinetics and binding affinities of anti-PD-1 antibody to human PD-1 determined by BLI.

Sample	Human PD-1
	Ka [1/M s)]	Kd [1/s]	KD [M]
HLX10	1.57 x 105	3.29 x 10−4	2.42 x 10−9
Nivo	1.28 x 105	1.50 x 10−3	11.9 x 10−9
Pembro	3.18 x 105	2.56 x 10−3	8.04 x 10−9
Sintilimab	1.44 x 105	3.00 x 10−4	2.09 x 10−9
Toripalimab	9.78 x 104	3.67 x 10−4	3.85 x 10−9