Figure 3.
APS promoted the phenotypic polarization from M1 to M2 of microglia in vitro. Relative mRNA expression levels of M1 polarization markers (TNF-α, iNOS, IL-12) and M2 polarization markers (Arg-1, IL-10, CD206) were detected by qRT-PCR (a–f). The protein expression of M1 polarization marker (iNOS) and M2 polarization marker (Arg-1) was detected by western blot (g). Compared with the CON group, ∗P < 0.05, ∗∗P < 0.01. Compared with the EAE group, #P < 0.05, ##P < 0.01.