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APS inhibited the mRNA level of IL-1α and C1q that induce activation of A1 astrocytes and in EAE mouse brain tissue (a, b) and suppressed the mRNA level of A1 astrocyte marker molecules C3 and GFAP (c, d) by qRT-PCR. Compared with the CON group, ∗P < 0.05, ∗∗P < 0.01; compared with the EAE group, #P < 0.05, ##P < 0.01.
