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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Neuroimage. 2021 Aug 14;242:118477. doi: 10.1016/j.neuroimage.2021.118477

Fig. 2.

Fig. 2.

Numerical simulation. (A) Spheres assigned either positive or negative susceptibility with various radius are drawn randomly in a voxel space. (B) Illustration of magnitude and phase signal progression for 3 simulated voxels with different combinations of assigned parameters.(C ~ E) Estimated parameters versus the ground truth are shown respectively. (E) The simulation results mostly are in a good agreement with ground truths. Results of χ that deviate the most from the ground truth are the cases when the concentration is low (C+or− < 0.1). (F) The composite paramagnetic component susceptibility (PCS) and diamagnetic component susceptibility (DCS) shows good agreement with the ground truth. (G) The magnetic field perturbation outside the spheres has negligible contribution to the total phase of the voxel as shown over 100 random simulations, which confirms the validity of the voxel field approximation.