Table 3.

Graft Failure and Mortality Outcomes Comparing NKR Chain End Recipients to non-NKR Living Donor and Deceased Donor Transplant Recipients.

	Chain End vs. Living Donor HR (95% CI)	p-value	Chain End vs. Deceased Donor HR (95% CI)	p-value
Death-Censored Graft Failure
Recipient Adjusted1	1.80 (1.32, 2.46)	<0.001	0.93 (0.69, 1.26)	0.6
Recipient + Donor Adjusted2	2.27 (1.37, 3.77)	<0.01	1.17 (0.73, 1.87)	0.5
Full Parsimonious Adjusted3	2.31 (1.38, 3.85)	<0.01	1.19 (0.74, 1.90)	0.5
Mortality
Recipient Adjusted	1.48 (1.12, 1.97)	<0.01	0.65 (0.49, 0.86)	<0.01
Recipient + Donor Adjusted	1.38 (0.92, 2.09)	0.1	0.61 (0.43, 0.87)	<0.01
Full Parsimonious Adjusted	1.39 (0.91, 2.13)	0.1	0.62 (0.43, 0.90)	0.01

¹Adjusted for recipient factors: female sex, African American race, Hispanic ethnicity, age, BMI>30 kg/m², diabetes, hypertension, history of transplant, college education, year of transplant, public insurance status, HCV, preemptive transplant, eGFR, and type of induction.

²Adjusted for recipient factors above and donor factors: BMI>30 kg/m², female sex, African-American race, Hispanic ethnicity, age, eGFR, and LKDPI/KDPI.

³Adjusted for recipient sex, recipient African-American race, recipient age, recipient BMI>30 kg/m², donor BMI>30 kg/m², recipient diabetes, history of previous transplant, donor sex, donor Hispanic ethnicity, year of transplant, recipient public insurance status, recipient HCV, donor age, preemptive transplant, recipient eGFR, type of induction, number of HLA mismatches, and LKDPI/KDPI.