Table 3.
Saline/vehicle rats behavioral outcomes (mean ± SEM).
| R0 (n = 8) | R14 (n = 9) | R28 (n = 4) | |
|---|---|---|---|
| Onset of meth effect | |||
| Horizontal activity | 916 ± 64 | 904 ± 62 | 707 ± 26 |
| Total distance | 413 ± 28 | 489 ± 35 | 493 ± 54 |
| Vertical activity | 227 ± 32 | 199 ± 30 | 164 ± 35 |
| Vertical time | 80 ± 23 | 52 ± 10 | 54 ± 16 |
| Vertical movement no | 35 ± 4 | 29 ± 3 | 29 ± 3 |
| Stereotypy count | 340 ± 21 | 348 ± 30 | 457 ± 51 |
| Stereotypy time | 60 ± 4 | 60 ± 4 | 63 ± 6 |
| Stereotypy no | 49 ± 2 | 50 ± 2 | 49 ± 2 |
| Peak meth effect | |||
| Horizontal activity | 904 ± 58 | 859 ± 45 | 827 ± 95 |
| Total distance | 385 ± 21 | 376 ± 22 | 369 ± 33 |
| Vertical activity | 263 ± 26 | 216 ± 30 | 199 ± 42 |
| Vertical time | 67 ± 10 | 57 ± 8 | 54 ± 13 |
| Vertical movement no | 39 ± 3 | 33 ± 3 | 34 ± 5 |
| Stereotypy count | 311 ± 19 | 344 ± 19 | 368 ± 25 |
| Stereotypy time | 56 ± 4 | 62 ± 3 | 64 ± 6 |
| Stereotypy no | 48 ± 1 | 50 ± 1 | 47 ± 1 |
Verification that the controls are similar across all time points. Capacity of meth to alter motor activity is the same regardless of when the animals received the vehicle.