Table 1.
CMR diagnosis |
P-value | ||||||
---|---|---|---|---|---|---|---|
All patients (n = 903) | No cardiac mass (n = 236) | Pseudomass (n = 149) | Thrombus (n = 146) | Benign tumour (n = 159) | Malignant tumour (n = 213) | ||
Age (years), median (IQR) | 60 (47–69) | 57 (45–68) | 67 (57–73) | 55 (43–65) | 63 (51–72) | 58 (46–66) | <0.001 |
Male sex, n (%) | 412 (45.6) | 119 (50.4) | 41 (27.5) | 87 (59.6) | 51 (32.1) | 114 (53.5) | <0.001 |
CAD risk factors | |||||||
Hypertension, n (%) | 535 (59.2) | 141 (59.7) | 101 (67.8) | 94 (64.4) | 102 (64.2) | 97 (45.5) | <0.001 |
Hyperlipidaemia, n (%) | 405 (44.9) | 112 (47.5) | 69 (46.3) | 89 (61.0) | 72 (45.3) | 63 (29.6) | <0.001 |
Diabetes mellitus, n (%) | 181 (20.0) | 49 (20.8) | 35 (23.5) | 40 (27.4) | 33 (20.8) | 24 (11.3) | 0.003 |
Smoking, n (%) | 359 (39.8) | 82 (34.7) | 73 (49.0) | 69 (47.3) | 54 (34.0) | 81 (38.0) | 0.008 |
Known CAD, n (%) | 239 (26.5) | 54 (22.9) | 34 (22.8) | 71 (48.6) | 40 (25.2) | 40 (18.8) | <0.001 |
Known extracardiac malignancy, n (%) | 286 (31.7) | 47 (19.9) | 27 (18.1) | 32 (21.9) | 23 (14.5) | 157 (73.7) | <0.001 |
CMR LVEF, median (IQR) | 60 (55–65) | 60 (55–65) | 61 (55–65) | 45 (25–60) | 65 (60–68) | 60 (55–65) | <0.001 |
Symptoms and signs, n (%) | |||||||
Dyspnoea | 307 (34.0) | 60 (25.4) | 44 (29.5) | 60 (41.1) | 37 (23.3) | 106 (49.8) | <0.001 |
Chest pain | 156 (17.3) | 29 (12.3) | 30 (20.1) | 24 (16.4) | 30 (18.9) | 43 (20.2) | 0.16 |
Palpitations | 30 (3.3) | 11 (4.7) | 4 (2.7) | 3 (2.1) | 4 (2.5) | 8 (3.8) | 0.68 |
Oedema | 51 (5.6) | 12 (5.1) | 8 (5.4) | 19 (13.0) | 5 (3.1) | 7 (3.3) | 0.001 |
Arrhythmia | 72 (8.0) | 21 (8.9) | 17 (11.4) | 14 (9.6) | 10 (6.3) | 10 (4.7) | 0.14 |
Pre-syncope | 19 (2.1) | 5 (2.1) | 0 (0.0) | 6 (4.1) | 3 (1.9) | 5 (2.3) | 0.14 |
Syncope | 36 (4.0) | 17 (7.2) | 3 (2.0) | 6 (4.1) | 6 (3.8) | 4 (1.9) | 0.045 |
Thromboembolism | 84 (9.3) | 33 (14.0) | 9 (6.0) | 19 (13.0) | 19 (11.9) | 4 (1.9) | <0.001 |
Other symptoms | 250 (27.7) | 51 (21.6) | 34 (22.8) | 26 (17.8) | 36 (22.6) | 103 (48.4) | <0.001 |
None | 207 (22.9) | 54 (22.9) | 40 (26.8) | 39 (26.7) | 42 (26.4) | 32 (15.0) | 0.025 |
Imaging preceding CMR, n (%) | |||||||
Echocardiography | 706 (78.2) | 206 (87.3) | 136 (91.3) | 119 (81.5) | 123 (77.4) | 122 (57.3) | <0.001 |
Computed tomography | 222 (24.6) | 22 (9.3) | 13 (8.7) | 14 (9.6) | 46 (28.9) | 127 (59.6) | <0.001 |
Plain radiography | 21 (2.3) | 4 (1.7) | 1 (0.7) | 0 (0.0) | 4 (2.5) | 12 (5.6) | 0.003 |
Coronary angiography | 35 (3.9) | 12 (5.1) | 2 (1.3) | 14 (9.6) | 3 (1.9) | 4 (1.9) | <0.001 |
Positron emission tomography | 36 (4.0) | 10 (4.2) | 0 (0.0) | 1 (0.7) | 1 (0.6) | 24 (11.3) | <0.001 |
None | 60 (6.6) | 12 (5.1) | 7 (4.7) | 22 (15.1) | 6 (3.8) | 13 (6.1) | <0.001 |
CAD, coronary artery disease; CMR, cardiovascular magnetic resonance; IQR, interquartile range; LVEF, left ventricular ejection fraction. P-values in bold are <0.05.