Table 2.
Adjusted hazard ratios (HRs) of cardiovascular and all-cause mortality according to presence of high-grade PVCs.
| Cardiovascular mortality (311 out of 5,486) | All-cause mortality (840 out of 5,486) | |||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Adjusted for age and sex | ||||
| Presence of high-grade PVCs during exercise | 1.16 (0.73–1.85) | 0.527 | 1.21 (0.90–1.62) | 0.217 |
| Presence of high-grade PVCs during recovery | 1.59 (1.09–2.30) | 0.015 | 1.28 (0.99–1.65) | 0.065 |
| Presence of high-grade PVCs during both exercise and recovery | 1.49 (0.79–2.83) | 0.222 | 1.65 (1.11–2.45) | 0.014 |
| Presence of high-grade PVCs during exercise or recovery | 1.42 (1.01–1.99) | 0.046 | 1.17 (0.93–1.47) | 0.189 |
| Adjusted for clinical variables * | ||||
| Presence of high-grade PVCs during exercise | 1.38 (0.82–2.34) | 0.224 | 1.26 (0.88–1.80) | 0.200 |
| Presence of high-grade PVCs during recovery | 1.82 (1.19–2.79) | 0.006 | 1.30 (0.96–1.75) | 0.092 |
| Presence of high-grade PVCs during both exercise and recovery | 1.49 (0.72–3.06) | 0.281 | 1.49 (0.93–2.40) | 0.101 |
| Presence of high-grade PVCs during exercise or recovery | 1.72 (1.17–2.53) | 0.006 | 1.24 (0.95–1.63) | 0.112 |
| Adjusted for clinical* and exercise test variables† | ||||
| Presence of high-grade PVCs during exercise | 1.34 (0.79–2.26) | 0.278 | 1.18 (0.83–1.69) | 0.356 |
| Presence of high-grade PVCs during recovery | 1.68 (1.09–2.60) | 0.020 | 1.15 (0.85–1.56) | 0.377 |
| Presence of high-grade PVCs during both exercise and recovery | 1.36 (0.66–2.80) | 0.405 | 1.31 (0.81–2.12) | 0.268 |
| Presence of high-grade PVCs during exercise or recovery | 1.63 (1.10–2.42) | 0.015 | 1.13 (0.86–1.49) | 0.375 |
Among those who experienced high-grade PVCs during exercise (N=101), 49 died from any cause, including 20 from cardiovascular causes.
Among those who experienced high-grade PVCs during recovery (N=133), 70 died from any cause, including 36 from cardiovascular causes.
Among those who experienced high-grade PVCs during both exercise and recovery (N=42), 26 died from any cause, including 10 from cardiovascular causes.
Among those who experienced high-grade PVCs during exercise or recovery (N=192), 93 died from any cause, including 46 from cardiovascular causes.
Clinical variables: age, sex, diabetes, hypertension, smoking, LDL- and HDL-cholesterol, triglycerides, body mass index, family history of premature coronary artery disease
Exercise test variables: exercise duration (in minutes), heart rate recovery (in beats per minute), achieving target heart rate, ST depression ≥ 1mm