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. 2021 Dec 1;113(6):421–426. doi: 10.32074/1591-951X-195

Figure 1.

Figure 1.

Merkel Cell Carcinoma. (A) (Hematoxylin & Eosin; x40) - Classic cytomorphology displaying small round blue cells with neuroendocrine chromatin, scant cytoplasm, and frequent mitoses. (B) (Immunohistochemistry; x40) - CK20, perinuclear dot pattern. (C) (Immunohistochemistry; x40) - Chromogranin A, granular cytoplasmic pattern. (D) (Immunohistochemistry; x20) - Synaptophysin, granular cytoplasmic pattern. (E) (Immunohistochemistry; x40) - PAX5, nuclear expression. (F) (Immunohistochemistry; x40) - Neurofilament, perinuclear dot pattern. (G) (Immunohistochemistry; x20) - MC Polyoma virus, nuclear expression. (H) (Immunohistochemistry; x20) - TDT, nuclear expression. (I) (Immunohistochemistry; x20) - NeuN, nuclear expression. (L) (Immunohistochemistry; x40) - NeuN, nuclear expression.