. 2021 Oct 1;113(5):307–315. doi: 10.32074/1591-951X-335

Table I.

Prognostic stratification models to predict clinical behavior of epithelioid angiomyolipoma.

Study	Classification	Criteria
Brimo et al.¹⁸	Benign epithelioid angiomyolipoma with atypia (≤ 2 adverse parameters)	1) ≥ 70% atypical epithelioid cells
Brimo et al.¹⁸		2) ≥ 2 mitotic figures per 10 HPF
	Malignant epithelioid angiomyolipoma with atypia (≥ 3 adverse parameters)	3) Atypical mitoses
		4) Detection of necrosis
Nese et al.¹⁹	Low-risk group (0-1 worrisome features)	1) Evidence of TSC and/or concurrent angiomyolipoma
Nese et al.¹⁹	Low-risk group (0-1 worrisome features)	2) Large tumor size (> 7 cm)
	Intermediate-risk group (2-3 worrisome features)	3) Histological pattern A
	Intermediate-risk group (2-3 worrisome features)	4) Extrarenal extension and/or involvement of renal vein
	High-risk group (4-5 worrisome features)	5) Detection of necrosis

Abbreviations: HPF: high power field; TSC: Tuberous Sclerosis Complex.