Summary of findings 3. Outreach treatment compared to hospital treatment for persons with an intellectual disability.

Outreach treatment compared to hospital treatment for persons with an intellectual disability
Patient or population: persons with an intellectual disability Setting: The Netherlands Intervention: outreach treatment Comparison: hospital treatment
Outcomes	No. of participants (studies)	Certainty of the evidence (GRADE)	Impact
Behavioural problems	49 (1 RCT)	⊕⊝⊝⊝ very low 1 2 3	It is uncertain whether outreach treatment decreases behavioural problems.
Care giver burden	49 (1 RCT)	⊕⊝⊝⊝ very low	It is uncertain whether outreach treatment decreases care giver burden.
Costs	49 (1 RCT)	⊕⊝⊝⊝ very low	It is uncertain whether outreach treatment decreases costs.
GRADE Working Group grades of evidence High certainty: We are very confident that the true effect lies close to that of the estimate of the effect Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect

¹ Downgraded for risk of bias as unclear allocation concealment and random sequence generation; surrogate main outcome; high risk of selective reporting.

² Downgraded for indirectness as main outcome was surrogate; generalisability of intervention unclear.

³ Downgraded for imprecision based on sample size and wide confidence intervals.