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. 2022 Jan 2;20:100365. doi: 10.1016/j.lanwpc.2021.100365

Table 2.

Treatment of patients admitted to a hospital in Japan for COVID-19 or influenza, as well as their length of stay.

COVID-19 (n=16,790) Influenza (n=27,870) p
Treatment on admission day, n (%)
ICU admission 749 (4·5) 207 (0·7) <0·0001
Oxygen therapy 3,707 (22·1) 7,938 (28·5) <0·0001
NPPV 34 (0·2) 119 (0·4) <0·0001
Mechanical ventilation 241 (1·4) 376 (1·4) 0·45
ECMO 6 (0·04) 9 (0·03) 0·85
Renal replacement therapy 108 (0·6) 168 (0·6) 0·60
Blood transfusion 167 (1·0) 67 (0·2) <0·0001
Vasopressor use 194 (1·2) 436 (1·6) <0·0001
Dexamethasone use 506 (3·0) 272 (1·0) <0·0001
Treatment during hospitalisation, n (%)
ICU admission 937 (5·6) 293 (1·1) <0·0001
Oxygen therapy 5,573 (33·2) 9,860 (35·4) <0·0001
NPPV 188 (1·1) 306 (1·1) 0·83
Mechanical ventilation 546 (3·3) 691 (2·5) <0·0001
ECMO 36 (0·2) 24 (0·1) <0·0001
Renal replacement therapy 407 (2·4) 395 (1·4) <0·0001
Blood transfusion 621 (3·7) 400 (1·4) <0·0001
Vasopressor use 609 (3·6) 891 (3·2) 0·015
Dexamethasone use 1,465 (8·7) 459 (1·7) <0·0001
Length of stay, median (IQR), days* 10 (7–16) 5 (4–10) <0·0001
Length of stay in ICU, median (IQR), days 3 (1–8) 4 (2–8) 0·089

Abbreviations: NPPV, Non-invasive Positive Pressure Ventilation; ECMO, extracorporeal membrane oxygenation; ICU, intensive care unit; IQR, interquartile range. Data are reported as number (%) for categorical variables and median (IQR) for continuous variables. We conducted the Mann-Whitney U test for continuous variables and the χ2 test for categorical variables.

Length of stay was calculated for patients discharged alive (15,934 for COVID-19 and 27,079 for influenza).

Length of stay in ICU was calculated for patients who stayed in ICU and discharged alive (658 for COVID-19 and 180 for influenza)