Table 2.
2-SC studied for the antioxidant activity and summary of the observed antioxidant effects. The table display the antioxidant activity shown for the studied 2-SC according to the criterion: activity greater or equal to 30%.
| 2-SC | Observed effect(s) | Ref. |
|---|---|---|
| 3 | Scavenging of DPPH• | [32] |
| 5 | Inhibition of XO and high oxidation potential | [22, 27] |
| 11 | Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; scavenging effect against ROS and RNS (O2•−; H2O2; HOCl; 1O2; ROO• and ONOO−); and moderate oxidation potential | [22, 24, 26, 27] |
| 13 | Inhibition of XO; scavenging effect against ROS (O2•− and HOCl); and high oxidation potential | [22, 26, 27] |
| 14 | Inhibition of XO; scavenging effect against ROS and RNS (HOCl; 1O2; ROO•; ONOO− and •NO); and high oxidation potential | |
| 15 | Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; scavenging effect against ROS and RNS (H2O2 and ONOO−); and moderate oxidation potential | [22, 24, 26, 27] |
| 16 | Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; scavenging effect against ROS and RNS (O2•−; HOCl; 1O2; ROO• and ONOO−); and moderate oxidation potential | |
| 17 - 19 | Inhibition of XO; protective activity against t-BHP-induced hepatotoxicity in rat hepatocytes; inhibition of Cu2+-induced oxidation of isolated human serum LDL; scavenging effect against ROS and RNS (O2•−; H2O2; HOCl; 1O2; ROO•; ONOO− and •NO); and low oxidation potential | [22, 24–27] |
| 20 | Inhibition of Cu2+-induced oxidation of isolated human serum LDL; scavenging effect against ROS and RNS (O2•−; H2O2; HOCl; 1O2; ROO•; ONOO− and •NO); and low oxidation potential | [25–27] |
| 21 | Scavenging effect against ROS and RNS (O2•−; HOCl; 1O2; ROO•; ONOO− and •NO); and moderate oxidation potential | [26, 27] |
| 22 - 24 | Scavenging effect against ROS and RNS (O2•−; H2O2; HOCl; 1O2; ROO•; ONOO− and •NO); metal chelating capacity; and reducing activity | [28] |
| 25 | Scavenging effect against ROS and RNS (O2•−; HOCl; 1O2; ROO•; ONOO−, without NaHCO3, and •NO) | [29] |
| 26, 27 | Scavenging effect against ROS and RNS (O2•−; HOCl; 1O2; ROO•; ONOO− and •NO) | |
| 28 - 32 | Scavenging of O2•− | [30] |
| 33 | Inhibition of reactive species-induced oxidation of DCFH-DA | [32] |
1O2: singlet oxygen; t-BHP: tert-butyl hydroperoxide; DCFH-DA: 2′,7′-dichlorodihydrofluorescein diacetate; DPPH•: 2,2-Diphenyl-1-picrylhydrazyl radical; H2O2: hydrogen peroxide; HOCl: hypochlorous acid; LDL: low-density lipoproteins; •NO: nitric oxide radical; ONOO−: peroxynitrite anion; RNS: reactive nitrogen species; ROS: reactive oxygen species; ROO•: peroxyl radical; O2•−: superoxide anion radical; XO: xanthine oxidase.