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. 2021 Nov 25;13(1):3–14. doi: 10.1111/1759-7714.14238

FIGURE 10.

FIGURE 10

Knockdown of LINC00460 affected OS progression by inducing the cell apoptosis via the decreasing the expression of cyclin D1, CDK4, and CDK6. Knockdown of LINC00460 inhibited cell migration through decreasing the MMP‐9 activity and suppressing the EMT process. 48 Knockdown of LINC00460 decreased the expression of FADS1 and increased miR‐1224‐5p regulating the cell proliferation and migration in OS. 49 Knockdown of LINC00460 suppressed NPC cell proliferation, migration, and invasion by targeting miR‐30a‐3p/Rap1A and miR‐149‐5p/IL6 50 , 51 ; LINC00460 promoted OC progression by binding miR‐338‐3p 52 ; LINC00460 prompted bladder urothelial carcinoma progression via sponging of miR‐612 by elevating FOXK1 expression 53 ; LINC00460 accelerated pancreatic cancer by binding to the suppressor miR‐491‐5p 54 ; knockdown of LINC00460 suppressed proliferation cervical cancer cells by targeting miR‐503‐5p and miR‐361‐3p/Gli1 axis 55 , 56