Skip to main content
. 2020 Jul 17;9(1):268–274. doi: 10.1016/j.gendis.2020.07.004

Figure 2.

Figure 2

Mettl5 regulates neural development in vitro. (A). Cell proliferation of Mettl5 KO and control mESC. (B). mRNA expression of stem cell markers in Mettl5 KO and control mESCs. (C). Volcano Plot of RNA-Seq data from Mettl5 KO and control mESCs. (D). Volcano Plot of RNA-Seq data from the Mettl5 KO and control embryonic bodies (differentiated for 6 days). (E). Gene ontology analysis of decreased expression genes in the Day6 Mettl5 KO embryonic bodies. (F). Gene ontology analysis of cross-comparison between control mESCs vs control embryonic bodies and Mettl5 KO mESCs vs Mettl5 embryonic bodies. (G). qRT-PCR analysis of mRNA expression in Mettl5 KO and control embryonic bodies (differentiated for 6 days). (H). Volcano Plot of RNA-Seq data from the Mettl5 KO and control cells (differentiated for 6 days in the N2B27 medium). (I). Gene ontology analysis of decreased expression genes in Mettl5 KO cells (differentiated for 6 days in the N2B27 medium). (J). qRT-PCR analysis of mRNA expression in Mettl5 KO and control cells (differentiated for 6 days in the N2B27 medium).