Table 1.

The coumarin derivatives with anti-CHIKV activity.

Compound	Chemical structure	CC50a (μM)	EC50b (μM)	SI
29		178	19.1	9.3
30		117	10.2	11.5
31		144	17.2	8.8
32		107	19.0	5.6
33		75.2	13.0	5.8
34		＞212	9.9	＞21.7
35		96.5	10.3	9.37
36		＞227	13.9	＞16.3
37		3150.0	10.7	295.2
38		549.8	0.5	1021.0

^aCC₅₀: the half cytotoxic concentration.

^bEC₅₀: the median effective concentration.