TABLE 1.
Resistance patterns of MDR-TB isolates from Brazil
| Isolate(s)a | Resistanceb |
|---|---|
| RS7591c | (R) RIF |
| SP16, SP17, SP18, SP24, SP26, SP27, SP28, RJ30, RJ32, RJ38, RS02, RS34, RS40, RS6562, RS6580, RS6756, RS6965, RS7084, RS7205, RS7242, RS7365, RS7484, RS7506, RS7543, RS8029, RS8142, RS8183, RS8187 | (R) RIF, INH |
| SP22, SP23, SP25, RJ35, RJ53, RS28, RS36, RS6886, RS7753, RS8117 | (R) RIF, INH, SM |
| SP03, SP04, SP06, SP07, SP10, SP11, SP15, RJ39, RJ50, RS6565, RS8001 | (R) RIF, INH, PZA |
| RS57, RS6782, RS7180, RJ42 | (R) RIF, INH, EMB |
| SP08, RJ41, RJ48, RS6573 | (R) RIF, INH, SM, PZA |
| RJ44, RS7681 | (R) RIF, INH, SM, EMB |
| SP13, RJ54, RS7704 | (R) RIF, INH, PZA, ETH |
| RS7253, RS7256, RS7454 | (R) RIF, INH, EMB, ETH |
| RJ49 | (R) RIF, INH, SM, PZA, ETH |
| RS07 | (R) RIF, INH, SM, EMB, ETH |
| RJ37, RJ40, RJ51, RJ52 | (R) RIF, INH, PZA, EMB, ETH |
| RJ29, RJ31, RJ33, RJ34, RJ46, RJ47, RJ55 | (R) RIF, INH, SM, PZA, EMB, ETH |
| RJ36, RS5897, RS6577, RS6569, RS6513, RS6514d | (S) RIF, INH, SM, EMB, ETH |
| SP19d | (R) INH; (S) RIF, EMB, ETH |
| RS16, RS20, RS21, RS7619d | (S) RIF, INH, PZA, EMB |
| RS7594d | (R) INH; (S) RIF, SM, EMB, ETH |
| RS6587, RS6676, RS6748d | (S) RIF, INH, SM, PZA, EMB |
| RS61025d | (S) RIF, INH, SM, PZA, EMB, ETH |
| RS8124d | (R) INH; (S) RIF, SM, PZA, EMB, ETH |
| RS8135d | (R) INH, PZA; (S) RIF, SM, EMB, ETH |
a
RS, isolates from RS State; RJ, isolates from RJ State; SP, isolates from SP State. The isolates with new rpoB alleles are indicated in bold. The Rifr isolates without mutation in the 157-bp region are underlined.
b
RIF, rifampin; INH, isoniazid; PZA, pyrazinamide; SM, streptomycin; EMB, ethambutol; ETH, ethionamide; (R), resistant; (S), susceptible.
c
Resistant only to rifampin.
d
Isolate(s) susceptible to rifampin.