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. 2021 Dec 20;12:799124. doi: 10.3389/fimmu.2021.799124

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Copyright © 2021 Dai, Wu, Cui, Liao, Jiao, Zhang, Song, Fan, Zhang, He and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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An increased frequency of platelet-CD4 ⁺ T cell aggregates is positively correlated with sCD14 and sCD163 during HIV-1 infection. (A) Serum level of sCD14 from HCs (n=19), TNs (n=28), IRs (n=21) and INRs (n=12). (B) Serum level of sCD163 from HCs (n=19), TNs (n=28), IRs (n=21) and INRs (n=12). (E) Frequencies of CD38⁺HLA-DR⁺CD4⁺T cell in CD4⁺ T cells from HCs (n=11), TNs (n=13), IRs (n=17) and INRs (n=11). Correlation between (C) plasma sCD14 levels (n=28), (D) plasma sCD163 levels (n=28), and (F) CD38⁺HLA-DR⁺CD4⁺ T cells (n=13) and the frequencies of platelet-CD4⁺ T cell aggregates in CD4⁺ T cells. *P < 0.05, **P ≤ 0.01, ***P ≤ 0.001, ****P ≤ 0.0001.