Table 1.
Top 20 significantly up-regulated and down-regulated circRNAs in SHR rat (|log2FoldChange| > 4, Q-value < 0.05).
| CircRNA | Q-value | log2FoldChange | Regulation | chrom | strand | CircRNA_type | GeneSymbol |
|---|---|---|---|---|---|---|---|
| rno_circRNA_0009301 | 1.51E-17 | 7.3709 | Up | chr20 | + | Exonic | – |
| rno_circRNA_0005304 | 2.28E-12 | 6.4932 | Up | chr17 | + | Intergenic | – |
| rno_circRNA_0008384 | 3.59E-09 | 5.9610 | Up | chr1 | – | Intergenic | – |
| rno_circRNA_0001706 | 8.23E-09 | 5.7243 | Up | chr11 | – | Exonic | Adcy5 |
| rno_circRNA_0000407 | 3.37E-06 | 5.0298 | Up | chr10 | – | Exonic | Snx29 |
| rno_circRNA_0010188 | 3.18E-06 | 5.0262 | Up | chr2 | + | Exonic | Frrs1 |
| rno_circRNA_0000489 | 3.56E-06 | 5.0107 | Up | chr10 | + | Exonic | Sap30l |
| rno_circRNA_0012471 | 4.90E-06 | 4.9696 | Up | chr4 | + | Exonic | RGD1565355 |
| rno_circRNA_0010453 | 7.82E-12 | 4.7779 | Up | chr2 | + | Exonic | Ddah1 |
| rno_circRNA_0012704 | 7.38E-05 | 4.5727 | Up | chr4 | – | Intergenic | – |
| rno_circRNA_0002616 | 1.42E-04 | 4.4966 | Up | chr12 | – | Exonic | Fry |
| rno_circRNA_0005818 | 2.48E-04 | 4.3747 | Up | chr17 | – | Exonic | Dnajc1 |
| rno_circRNA_0009971 | 3.39E-04 | 4.3142 | Up | chr2 | + | Exonic | Arnt |
| rno_circRNA_0018260 | 4.52E-04 | 4.2612 | Up | chr9 | – | Exonic | Smap1 |
| rno_circRNA_0004376 | 5.72E-04 | 4.2419 | Up | chr15 | + | Exonic | Scara5 |
| rno_circRNA_0005506 | 1.10E-03 | 4.1191 | Up | chr17 | – | Exonic | Ryr2 |
| rno_circRNA_0011085 | 1.09E-03 | 4.1051 | Up | chr3 | – | Exonic | Fbn1 |
| rno_circRNA_0011717 | 1.89E-03 | 3.9862 | Up | chr3 | – | Exonic | Golga1 |
| rno_circRNA_0018702 | 2.53E-03 | 3.9256 | Up | chr9 | – | Exonic | Bard1 |
| rno_circRNA_0004164 | 2.48E-03 | 3.921 | Up | chr15 | + | Exonic | Samd4a |
| rno_circRNA_0018394 | 1.70E-15 | 7.0728 | Down | chr9 | + | Exonic | Bivm |
| rno_circRNA_0018389 | 1.91E-10 | 6.1736 | Down | chr9 | – | Exonic | Kdelc1 |
| rno_circRNA_0002969 | 4.17E-08 | 5.633 | Down | chr13 | – | Exonic | Cfh |
| rno_circRNA_0006911 | 1.80E-07 | 5.4753 | Down | chr19 | + | Exonic | Spg7 |
| rno_circRNA_0006284 | 3.86E-07 | 5.3752 | Down | chr18 | + | Exonic | Wdr7 |
| rno_circRNA_0001637 | 5.32E-07 | 5.3332 | Down | chr11 | – | Intronic | Ccdc80 |
| rno_circRNA_0010322 | 1.05E-06 | 5.2562 | Down | chr2 | – | Exonic | Npnt |
| rno_circRNA_0014612 | 2.86E-06 | 5.1309 | Down | chr5 | + | Exonic | Rgs3 |
| rno_circRNA_0012056 | 5.79E-10 | 5.064 | Down | chr3 | + | Intergenic | – |
| rno_circRNA_0015320 | 4.61E-06 | 5.0522 | Down | chr6 | – | Exonic | Hadhb |
| rno_circRNA_0019038 | 1.02E-18 | 4.8343 | Down | chrX | + | Intergenic | – |
| rno_circRNA_0001500 | 5.59E-05 | 4.7371 | Down | chr11 | + | Intronic | Ttc3 |
| rno_circRNA_0019050 | 0.000147 | 4.5686 | Down | chrX | – | Intergenic | – |
| rno_circRNA_0000840 | 0.000236 | 4.481 | Down | chr10 | – | Exonic | Rph3al |
| rno_circRNA_0009286 | 0.000223 | 4.4693 | Down | chr20 | – | Exonic | Psmb9 |
| rno_circRNA_0008598 | 0.000325 | 4.4257 | Down | chr1 | – | Exonic | AABR07007032.1 |
| rno_circRNA_0007580 | 0.000423 | 4.3558 | Down | chr1 | + | Exonic | Pde3b |
| rno_circRNA_0009197 | 4.79E-08 | 4.1701 | Down | chr20 | – | Exonic | Cdh23 |
| rno_circRNA_0011093 | 0.001512 | 4.1075 | Down | chr3 | + | Exonic | Slc27a2 |
| rno_circRNA_0017128 | 0.001937 | 4.0647 | Down | chr8 | + | Exonic | Snrk |
circRNAs, circular RNAs; SHR, spontaneously hypertensive rats; Chrom, chromosome; Adcy5, adenylate cyclase 5; Fbn1, fibrillin-1; Cfh, complement factor H.