TABLE 1.
Agonists at H2-histamine-receptors.
| Agonist name | pD2 | Tissue studied | References |
|---|---|---|---|
| Compound 16 | 9.61 | Sf9 insect cells expressing the human H2R | Birnkammer et al. (2012) |
| Apromidine | 8.0 | Guinea pig isolated right atrial preparations | Buschauer (1989) |
| BU-E-76 | 37.91 | 1,2 In vivo haemodynamic of guinea pig left ventricle | 1 Felix et al. (1991a), 2 Felix et al. (1995) |
| 3Guinea pig isolated right atrial preparations | |||
| 3 Buschauer and Baumann (1991) | |||
| BU-E-75 | 37.90 | 1,2 In vivo haemodynamic of guinea pig left ventricle | 1 Felix et al. (1991a), 2 Felix et al. (1995) |
| 3Guinea pig isolated right atrial preparations | |||
| 3 Buschauer and Baumann (1991) | |||
| Amthamine | 7.04 | Guinea pig isolated right atrial preparations | Eriks et al. (1992) |
| Impromidine | 7.04 | Guinea pig isolated right atrial preparations | Bertaccini and Coruzzi (1981) |
| 4-Methyl-histamine | 7.01 | pH measurement in isolated perfused rat stomach | Durant et al. (1975) |
| Dimaprit | 16.19 | 1Guinea pig isolated right atrial preparations | 1 Parsons et al. (1977) |
| 2Guinea pig hippocampal slices | 2 Garbarg and Schwartz (1988) | ||
| 3CHO cells expressing the rat H2-histamine-receptor | 3 Smit et al. (1996a) | ||
| Histamine | 16.60 | Guinea pig isolated right atrial preparations | 1 Bertaccini and Coruzzi (1981) |
| 26.00 | 2 Buschauer and Baumann (1991) |
Synopsis of some relevant histamine agonists (first column), their affinity at H2-histamine receptors (decadic logarithms of their affinity constants, second column), the tissue studied (third column) and the references (fourth column).