Table 1.
Baseline characteristics of study subjects.
| Variables | n = 72 |
|---|---|
| Age (years) | 46.8 ± 14.8 |
| Male, n (%) | 41 (56.9) |
| Preoperative height (cm) | 164.0 ± 9.6 |
| Preoperative body weight (kg) | 69.1 ± 13.0 |
| Preoperative BMI (kg/m2) | 25.3 (22.7–27.2) |
| Postoperative body weight (kg) | 72.0 ± 13.0 |
| Postoperative BMI (kg/m2) | 25.9 (23.9–28.3) |
| Follow-up duration (days) | 764 (479–1724) |
| Body weight change (kg) | 3.0 (-0.9–6.2) |
| % body weight change (%) | 4.4 (-1.1–10.1) |
| BMI change (kg) | 1.3 (-0.3–2.4) |
| % BMI change (%) | 4.4 (-1.1–10.0) |
| Previous history of surgery or irradiation for craniopharyngioma | 16 (22.2) |
| Duration of steroid replacement (days) | 719 (232–1456) |
| Daily steroid dose (mg/day) a | 12.9 (10.9–15.3) |
| Cumulative steroid dose (mg) a | 7295 (2962–12309) |
| Preoperative tumor volume (cm3) | 4.6 (2.1–10.5) |
| Postoperative corrected hypothalamic volume b | 0.042 ± 0.011 |
| Preoperative visual disturbance, n (%) | 52 (72.2) |
| Postoperative visual disturbance status | |
| Aggravation | 4 (5.6) |
| No change | 14 (19.4) |
| Improvement | 50 (69.4) |
| Non-applicable | 4 (5.6) |
| Preoperative hormone deficiency | |
| 0 | 17 (24.6) |
| 1 | 16 (22.2) |
| 2 | 8 (11.1) |
| 3 | 1 (1.4) |
| 4 | 30 (41.7) |
| Postoperative hormone deficiency | |
| 0 | 5 (6.9) |
| 1 | 3 (4.2) |
| 2 | 0 (0.0) |
| 3 | 0 (0.0) |
| 4 | 64 (88.9) |
| Postoperative diabetes insipidus, n (%) | 62 (86.1) |
| Preoperative hypothalamic symptom, n (%) | 25 (34.7) |
| Postoperative hypothalamic symptom, n (%) | 9 (12.5) |
Data are expressed as mean ± SD or median (interquartile range) or n (%). BMI, body mass index.
a
Hydrocortisone-equivalent dose of steroid.
b
Corrected hypothalamic volume = measured hypothalamic volume/temporal lobe volume.