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. 2021 Dec 31;14(12):e245405. doi: 10.1136/bcr-2021-245405

Table 3.

Treatment and outcome details in patients with COVID-19 related CVST undergoing mechanical thrombectomy

Cases Current case Case A Case B
Treatment for COVID-19 Nil Lopinavir - Ritonavir Lopinavir - Ritonavir
Treatment for CVST (pharmacological) Enoxaparin 60 mg S/C twice daily Enoxaparin 70 mg S/C twice daily Unfractionated heparin 1000 units per hour as continuous infusion
Treatment for CVST (surgical) Mechanical thrombectomy of superior sagittal sinus Mechanical thrombectomy of superior sagittal sinus and subsequent catheter based continuous r-TPA infusion at 2 mg/hour Intrasinus thrombosis with r-TPA 20 mg slowly into superior sagittal sinus followed by mechanical thrombectomy; later underwent decompressive craniotomy on 8th day
Time duration between symptoms and endovascular therapy for CVST On 5th day of admission Within 24 hours On 4th day of admission
Duration of admission 18 days 32 hours 10 days
Outcome Discharged home with minimal deficits Death after 32 hours of admission Death after 10 days
Cause of death (if applicable) N/A Respiratory failure and cardiac arrest Septic shock and DIC