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. 2021 Dec 20;12:741087. doi: 10.3389/fphar.2021.741087

FIGURE 5.

FIGURE 5

High-salt diet alters SGLT2 and Na+/K + -ATPase expression in renal tubules of DKD mice. (A) Expression of SGLT2 gene in renal tubules (n = 6 per group). (B) Paraffin-embedded renal sections were stained with SGLT2, ATP1A1 and ATP1B1 antibodies (magnification, 400×, bar = 20 μm). (C) Histopathological assessment of SGLT2, ATP1A1 and ATP1B1 proteins (n = 4 per group). All data are mean ± SEM, *p < 0.05, **p < 0.01 and ***p < 0.001 vs. Control group; ##p < 0.01 and ###p < 0.001 vs. DM group.