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. 2021 Dec 20;12:747738. doi: 10.3389/fimmu.2021.747738

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Copyright © 2021 Steininger, Rossmanith, Geier, Leiss-Piller, Thonhauser, Weiss, Hainfellner, Freilinger, Schmidt, Eibl and Wolf

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cerebral magnetic resonance imaging (cMRI) of the index patient at age 10. (A, B) T1-weighted, contrast enhanced MRI scans in coronal (A) and axial (B) plane depicting the hypertrophic pachymeningitis with bilateral basal ganglia, midbrain and cortical lesions. Note the postinfectious internal hydrocephalus. (C) 3D reconstitution of the vascular system of the brain showing bilateral media aneurysms and a posterior cerebral artery aneurysm on the right without signs of vessel narrowing. (D) T2-weighted MRI scan in coronal plane highlighting the extensive frontotemporal white matter edema on the left, global parenchymal atrophy and the medial cerebral artery aneurysms bilaterally.