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. 2021 Dec 20;12:809208. doi: 10.3389/fimmu.2021.809208

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Copyright © 2021 Yang, Wu, Sun, Fang, Liu, Ji, Park, Qin, Yang and Wang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summarized functional feature of innate-adaptive immunological interplay of Ly6C MC in CT and ApoE ^-/- mice. Model summarized functional changes derived from molecule signaling presented in Figures 5 – 7 . (A) Innate/adaptive immunological feature of Ly6C^high MC subsets in CT mice. (B) Innate/adaptive immunological feature of Ly6C^high MC subsets in ApoE ^-/- mice. (C) ApoE ^-/–induced innate/adaptive immunological feature of Ly6C^high MC subsets. (D) Inflammatory and atherogenic functional balance in Ly6C MC. APC, antigen presenting cell; TCR, T cell receptor.