Table 2.

Geometric mean concentrations (GMC) and geometric mean titers (GMT) to pneumococcal serotypes before and at one, six and twelve months after administration of 13-valent pneumococcal conjugate vaccine (PCV13) in 38 HIV-infected subjects with CD4 cell count ≥200 cells/µl.

Serotype	ELISA GMC								OPA GMT
	M0		M1		M6		M12		M0		M1		M6		M12
	GMC (µg/mL)	(95% CI)	GMC (µg/mL)	(95% CI)	GMC (µg/mL)	(95% CI)	GMC (µg/mL)	(95% CI)	GMT	(95% CI)	GMT	(95% CI)	GMT	(95% CI)	GMT	(95% CI)
4	0.6	(0.4-0.7)	1.9	(1.4-2.8)	1.0	(0.8-1.4)	0.8	(0.6-1.1)	8.3	(4.3-15.9)	169.9	(80.6-357.8)	37.6	(15.8-89.3)	36.3	(16.9-77.9)
6B	1.7	(1.2-2.4)	4.1	(2.7-6.2)	2.8	(1.8-4.2)	2.5	(1.7-3.8)	18.1	(9.1-35.8)	390.7	(186.3-819.5)	171.7	(83.6-352.5)	111.6	(54.9-226.9)
9V	1.0	(0.6-1.6)	2.3	(1.5-3.6)	1.5	(1.0- 2.2)	1.3	(0.8-2.0)	13.0	(7.3-23.1)	183.6	(94.8-355.7)	81.2	(37.6-175.0)	51.9	(23.9-112.7)
14	4.2	(2.5-7.0)	10.6	(6.6-17.0	7.6	(4.7-12.3)	7.6	(4.9-12.0)	42.8	(17.0-107.9)	473.7	(206.1-1089.1)	241.7	(97.9-596.3)	223.4	(98.8-505.4)
18C	0.9	(0.6-1.3)	3.0	(2.1-4.3)	1.7	(1.2-2.4)	1.6	(1.1-2.3)	19.6	(9.8-39.7)	309.1	(163.8-583.3)	120.6	(57.0)-255.5)	89.3	(43.8-182.2)
19F	2.8	(2.0-3.9)	6.6	(4.8-9.0)	3.7	(2.6-5.2)	2.9	(1.9-4.3)	31.1	(14.8-65.7)	287.9	(144.2-574.7)	130.7	(60.9-280.7)	124.9	(66.2-235.3)
23F	1.3	(0.9-1.9)	3.6	(2.3-5.7)	2.4	(1.4-4.0)	1.6	(0.9-2.8)	14.0	(6.1-31.8)	222.9	(80.3-618.4)	90.7	(28.8-286.0)	79.4	(28.2-223.6)
7F	1.1	(0.7-1.9)	3.8	(2.4-6.1)	2.6	(1.7-4.1)	1.8	(1.2-2.9)
10A*	1.3	(0.7-2.3)	1.3	(0.7-2.3)	1.2	(0.7-2.3)	1.1	(0.6-2.0)
15B*	1.8	(1.0-3.2)	2.2	(1.3-3.7)	1.8	(1.0-3.1)	1.8	(1.1-3.0)

CI, confidence intervals.

GMC, geometric mean concentrations; GMT, geometric mean titers.

*Targeted by PPV23 but not PCV13.