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. 2021 Dec 29;14:3909–3918. doi: 10.2147/JPR.S344568

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© 2021 Vallejo et al.

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Evoked compound action potential (ECAP) amplitudes (top row) and multi-program charge/phase (bottom row) for both open-loop (OL, left) and closed-loop (CL, right) stimulation in a representative subject. Stimulation charge/phase, or Q/ph (expressed as micro-coulombs/stimulation phase) is the product of stimulation amplitude (in milliamps) and stimulation pulse width (in milliseconds). The subject is asked to perform motions of daily living in both the OL and CL configurations, with the resultant variability in ECAP amplitude—an indicator of variability in neural activation—assessed.