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. 2021 Dec 20;12:755825. doi: 10.3389/fphar.2021.755825

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Copyright © 2021 Belo, Cordeiro, Oliveira, Braga, da Silva, Costa, Martins, Jan, Le Loir, Gala-García, Ferreira, Azevedo and do Carmo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Lactococcus lactis-Surface-layer protein (Slp)B is able to control weight loss in Dextran Sulfate Sodium (DSS)-induced colitis. Time-course of body weight during the seven experimental days (A) and weight loss (B) are shown. The two-way ANOVA (A), one-way ANOVA (B), and Tukey’s post-hoc tests were used for the multiple comparisons (The data represent the mean ± SD of 12 mice per group). Asterisks represent statistically significant differences as follows: ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001.