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. 2021 Dec 20;12:755825. doi: 10.3389/fphar.2021.755825

FIGURE 2.

FIGURE 2

L lactis-SlpB alleviates clinical symptoms in DSS-colitis mice model and reduces colon mucosal damage. Disease activity index over the seven experimental days (A), at the last day (B), Colon length analysis (C), Micrograph images of the histopathological analysis of the colon tissue (D) and analysis of the histopathological score (E) are shown. The slides were stained in hematoxylin and eosin (H&E) and analyzed under ×20 magnification. The two-way ANOVA (A), one-way ANOVA (B), and Tukey’s post-hoc tests were used for the multiple comparisons (The data represent the mean ± SD of 12 mice per group). Asterisks represent statistically significant differences as follows: ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001.