Table 2.
Stimulants in the in vitro assay.
| Stimuli | Receptor | Target cell |
|---|---|---|
| US | All | |
| PHA | TCR | T-cell |
| PWM | BCR | B-cell, (T-cell) |
| Isoproterenol | β-AR | T-cell |
| Pam3CSK4 | TLR1/2 | Monocyte, (B-cell) |
| Poly I:C-LMW | TLR3 | T-cell |
| LPS | TLR4 | Monocyte |
| ORN | TLR7 | Monocyte, (B-cell) |
| CpG ODN | TLR9 | B-cell |
| PepTivator EBV EBNA-1 | TCR/BCR | T-cell, B-cell |
β-AR, β-adrenergic receptor; BCR, B-cell receptor; CpG ODN, CpG oligodeoxynucleotides; LPS, Lipopolysaccharide; ORN, orioribonucleotid; Pam3CSK4, Pam3CysSerLys4; PepTivator EBV EBNA-1, PepTivator Epstein Barr Virus Epstein–Barr nuclear antigen-1; PHA, phytohemagglutinin; Poly I:C-LMW, Polyinosinic-polycytidylic acid-low molecular weight; PWM, pokeweed mitogen; TCR, T-cell receptor; TLR, Toll-like receptor; US, unstimulated.