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. 2021 Dec 20;12:759040. doi: 10.3389/fphar.2021.759040

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Copyright © 2021 Liu, Wang, Li, Hu, Xu, Wu, Bai, Ping, Lan and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of methyl gallate on NLRP3 pathway in renal tissues. (A) Representative western blot analysis of NLRP3, ASC, caspase-1 and IL-1β in renal tissues of mice in different groups. (B–E) Western blotting analysis of NLRP3, ASC, caspase-1 and IL-1β in renal tissues of mice in different groups. Values are expressed as means ± S.D. (n = 3). Data were analyzed by single-factor ANOVA with Tukey HSD test. Compared with control group: ^### p < 0.001; Compared with vehicle group: ^* p < 0.05, ^** p < 0.01., ^*** p < 0.001. MG: methyl gallate.