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. 2021 Apr 15;35:279–294. doi: 10.1016/j.jare.2021.04.003

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© 2021 The Authors. Published by Elsevier B.V. on behalf of Cairo University.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Fig. 1 — Plots showing the effect of PFOA on biological processes and functions of mouse liver through interference of gene expression. This comparative transcriptomic analysis demonstrates differential gene expression caused by PFOA (Control vs PFOA group). (a) DEGs evaluated by the Gene Ontology (GO) enrichment analysis. The rich factor plot exhibits the PFOA-altered biological processes (p < 0.05). (b) IPA-Tox of Ingenuity Pathway Analysis (IPA) data demonstrating the hepatotoxicity from PFOA (p < 0.05).

Fig. 1 — Plots showing the effect of PFOA on biological processes and functions of mouse liver through interference of gene expression. This comparative transcriptomic analysis demonstrates differential gene expression caused by PFOA (Control vs PFOA group). (a) DEGs evaluated by the Gene Ontology (GO) enrichment analysis. The rich factor plot exhibits the PFOA-altered biological processes (p < 0.05). (b) IPA-Tox of Ingenuity Pathway Analysis (IPA) data demonstrating the hepatotoxicity from PFOA (p < 0.05).