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. 2021 Apr 15;35:279–294. doi: 10.1016/j.jare.2021.04.003

Fig. 4.

Fig. 4

Evidence of vitamin C relief of PFOA-induced hepatotoxicity via changes of metabolites in the liver. The comparative metabolomic analysis used for determining the metabolites changes involved in the vitamin C protection on PFOA-induced hepatotoxicity (PFOA vs vitamin C + PFOA group). GO analysis highlighting reduced linoleic acid metabolism involvement in the vitamin C-relief of PFOA-induced hepatotoxicity.