Table 2.
Estimated risk for headache according to patient sociodemographic and clinical characteristics
| Characteristics | Headache N = 199 |
Without headache N = 89 |
Total N = 288 |
p value | Raw OR (95% CI) | Adjusted OR (95% CI)a |
|---|---|---|---|---|---|---|
| Female sex, n (%) | 111 (55.8) | 24 (27) | 135 (49.9) | < 0.01 | 3.42 (1.98–5.90) | 3.13 (1.64—5.97) |
| Aged > 50 years, n (%) | 91 (45.7) | 53 (59.6) | 144 (50) | 0.03 | 0.57 (0.35—0.95) | 0.97 (0.95—1.01) |
| Comorbidity, n (%) | 151 (75.9) | 61 (68.5) | 212 (73.6) | 0.19 | 1.44 (0.83—2.51) | – |
| FLU SYMPTOMS: | ||||||
| Fever, n (%) | 157 (78.9) | 42 (47.2) | 199 (69.1) | < 0.01 | 4.18 (2.44—7.16) | 3.99 (2.10—7.63) |
| Chills, n(%) | 95 (47.7) | 24 (27) | 119 (41.3) | < 0.01 | 2.47 (1.44—2.47) | – |
| Cough, n(%) | 141 (10.9) | 55 (61.8) | 196 (68.1) | 0.13 | 1.50 (0.89—2.54) | – |
| Sore throat, n(%) | 92 (46.2) | 11 (12.4) | 103 (35.8) | < 0.01 | 6.10 (3.06—12.16) | 3.69 (1.71—7.93) |
| Dyspnoea, n (%) | 159 (79.9) | 64 (71.9) | 223 (77.4) | 0.13 | 1.55 (0.87—2.77) | – |
| Chest pain, n (%) | 83 (41.7) | 16 (18) | 99 (34.4) | < 0.01 | 3.27 (1.77—6.01) | – |
| Low oxygenation, n (%) | 111 (55.8) | 54 (60.7) | 165 (57.3) | 0.44 | 0.82 (0.49—1.36) | – |
| Cyanosis, n (%) | 20 (10.1) | 5 (5.6) | 25 (8.7) | 0.22 | 1.88 (0.68—5.17) | – |
| Coryza, n (%) | 80 (40.2) | 19 (21.3) | 99 (34.4) | < 0.01 | 2.48 (1.39—4.43) | – |
| Joint pain, n (%) | 87 (43.7) | 16 (18) | 103 (35.8) | < 0.01 | 3.54 (1.93—6.52) | – |
| Diarrhea, n (%) | 91 (45.7) | 20 (22.5) | 111 (38.5) | < 0.01 | 2.91 (1.64—5.14) | – |
| Nausea, n (%) | 80 (40.2) | 14 (15.7) | 94 (32.6) | < 0.01 | 3.60 (1.91—6.81) | – |
| Vomiting, n (%) | 56 (28.1) | 11 (12.4) | 67 (23.3) | < 0.01 | 2.78 (1.38—5.61) | – |
| Abdominal pain, n (%) | 61 (30.7) | 9 (10.1) | 70 (24.3) | < 0.01 | 3.93 (1.85—8.34) | – |
| Flu, n (%) | 198 (99.5) | 78 (87.6) | 276 (95.8) | < 0.01 | – | – |
| SARS, n (%) | 199 (100) | 83 (93.3) | 282 (97.9) | < 0.01 | – | – |
| NEUROLOGICAL SYMPTOMS: | ||||||
| Anosmia/Ageusia, n (%) | 160 (80.4) | 48 (53.9) | 208 (72.2) | < 0.01 | 3.50 (2.03—6.04) | 1.94 (1.01—3.73) |
| Myalgia, n (%) | 107 (53.8) | 21 (23.6) | 28 (44.4) | < 0.01 | 3.77 (2.15—6.61) | 2.40 (1.26—4.59) |
| Fatigue, n (%) | 150 (75.4) | 46 (51.7) | 196 (68.1) | < 0.01 | 2.86 (1.69—4.84) | 1.56 (0.82—2.99) |
| Somnolence, n (%) | 80 (40.2) | 27 (30.3) | 107 (37.2) | 0.11 | 1.54 (0.91—2.63) | – |
| Confusion, n (%) | 26 (13.1) | 17 (19.1) | 43 (14.9) | 0.18 | 0.64 (0.33—1.24) | – |
| Agitation, n (%) | 41 (20.6) | 19 (21.3) | 60 (20.8) | 0.89 | 0.96 (0.52—1.76) | – |
| Syncope, n (%) | 7 (3,5) | 7 (7.9) | 14 (4.9) | 0.11 | 0.43 (0.15—1.26) | – |
| Seizure, n (%) | 7 (3,5) | 1 (1.1) | 8 (2.8) | 0.25 | 3.21 (0.39—26.47) | – |
Variables considered to the model: sex, age, fever, chills, sore throat, chest pain, coryza, joint pain, diarrhea, nausea, vomiting, abdominal pain, flu, SARS, anosmia/ageusia, myalgia, fatigue
aFinal Model: myalgia, anosmia/ageusia, sex, sore throat, fever, fatigue, and age