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Schematic representation of the oncogenic process in immunocompetent and immunodeficient individuals. Insights in non-redundant immune mechanisms for the control of oncoviruses gained from the study of inborn errors of immunity are listed in the upper right box. Most of them come from the genetic studies of HPV, EBV, and to lesser extend HHV8 infections. Genetic factors predisposing to severe HBV, HCV, MCPyV and HTLV1 remain largely unknown.
