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. 2021 Dec 21;8:2333794X211065330. doi: 10.1177/2333794X211065330

Table 4.

Results of Various Studies3,21 Related to the Future Treatments of SSPE Including Fusion Inhibitor Peptides, RNA Polymerase Inhibitors and Neutralizing Antibody-Derived Molecules.

Study name Author (s) Location Study type Result (s)
Subacute sclerosing panencephalitis 3 Ravindra Kumar Garg, Anita Mahadevan, Hardeep Singh Malhotra Imran Rizvi, Neeraj Kumar, Ravi Uniyal India Review Fusion inhibitor peptides (compound AS-48) that bind to the viral fusion proteins are being developed as potential therapeutic agents
Advances in antiviral therapy for subacute sclerosing panencephalitis 21 Koichi Hashimoto, Mitsuaki Hosoya Japan Review An RNA-Polymerase inhibitor, Favipiravir could also be exploited for the treatment of SSPE in the future
Advances in antiviral therapy for subacute sclerosing panencephalitis 21 Koichi Hashimoto, Mitsuaki Hosoya Japan Review Neutralizing antibody-derived molecules such as single-strand variable fragments that target the H protein are possible candidates for the treatment of SSPE