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. 2021 Dec 17;17:17448069211066221. doi: 10.1177/17448069211066221

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© © The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 1. — Spinal sPLA₂ activity is elevated at days 7 and 14 after a painful nerve root compression and is attenuated at day 14 following spinal sPLA₂ inhibition given at day 7. (a) Spinal sPLA₂ activity at day 7 after a painful nerve root compression (NRC) is significantly elevated (p = 0.005) over sham control levels. (b) Inhibitor treatment at day 7 significantly reduces (*p = 0.026) spinal sPLA₂ activity to sham levels on day 14. Spinal sPLA₂ activity after NRC with vehicle treatment is also significantly higher (#p = 0.035) than for sham.