. Author manuscript; available in PMC: 2022 Jan 3.

Published in final edited form as: Acc Chem Res. 2021 Nov 30;54(24):4545–4564. doi: 10.1021/acs.accounts.1c00573

Table 2.

Substrate Scope of Enantioselective HV of 1,3-Dienes

no.	R⁴	ligand	yield %	ee % (config.)
1.	Me	(R,R)-DIOP	95	95 (S)
2.	C₅H₁₁	(R,R)-DIOP	95	95 (S)
3.	C₅H₁₁	(S,S)-BDPP	96	96 (S)
4.	CyHex	(S,S)-DIOP	49	84 (R)
5.	BnOCH₂CH₂	(S,S)-BDPP	95	97 (R)
6.	BrCH₂CH₂	(S,S)-DIOP	97	93 (R)
7.	EtOC(O)CH₂	(S,S)-BDPP	84	98 (S)

See Figure 3 A for procedure.