Table I.
Correlation between GIMAP2 expression and the clinical classification of oral squamous cell carcinoma.
| Results of immunostaining No. of patients (%) | ||||
|---|---|---|---|---|
|
|
||||
| Variable | Total | GIMAP2 negative | GIMAP2 positive | P-value |
| Age at surgery (years) | ||||
| >70 | 41 | 14 (34) | 27 (66) | 0.580a |
| 60-70 | 35 | 16 (46) | 19 (54) | |
| <60 | 24 | 10 (42) | 14 (58) | |
| Sex | ||||
| Male | 57 | 21 (37) | 36 (63) | 0.458a |
| Female | 43 | 19 (44) | 24 (56) | |
| T-primary tumor | ||||
| T1+T2 | 51 | 32 (63) | 19 (37) | 0.0004a,b |
| T3+T4 | 49 | 8 (16) | 41 (84) | |
| N-regional lymph node | ||||
| Negative | 63 | 24 (38) | 39 (62) | 0.612a |
| Positive | 37 | 16 (43) | 21 (57) | |
| Stage | ||||
| I | 15 | 10 (67) | 5 (33) | 0.004a,b |
| II | 20 | 12 (60) | 8 (40) | |
| III | 18 | 7 (39) | 11 (61) | |
| IV | 47 | 11 (23) | 36 (77) | |
| Histopathologic type | ||||
| Good | 68 | 28 (41) | 40 (59) | 0.811a |
| Moderate | 28 | 11 (39) | 17 (61) | |
| Poor | 4 | 1 (25) | 3 (75) | |
| Vascular Invasion | ||||
| Negative | 62 | 24 (39) | 38 (61) | 0.737a |
| Positive | 38 | 16 (42) | 22 (58) | |
a
χ2 test;
b
P<0.05. GIMAP2, GTPase of immunity-associated protein 2.