Table 5.
Logistic regression analyses of iodine status with infant allergy diagnosis at 12 months of age.
| Biomarker or intake per 10 μg | n | Food allergy OR (95% CI) | p | n | Atopic eczema OR (95% CI) | p | n | Asthma OR (95% CI) | p |
|---|---|---|---|---|---|---|---|---|---|
| UNADJUSTED | |||||||||
| Dietary intake, μg/d (GW34) | 381/3702 | 0.94 (0.88–1.01) | 0.11 | 32/370 | 1.00 (0.93–1.06) | 0.89 | 32/370 | 0.96 (0.88–1.02) | 0.22 |
| Maternal urine, μg/L (GW29) | 38/380 | 1.03 (0.99–1.06) | 0.10 | 33/380 | 1.03 (0.99–1.07) | 0.07 | 34/380 | 0.95 (0.89–1.01) | 0.12 |
| Dietary intake, μg/d (4M) | 37/373 | 0.94 (0.87–1.00) | 0.07 | 31/373 | 0.99 (0.92–1.05) | 0.68 | 32/373 | 0.91 (0.83–0.98) | 0.02 |
| Breast milk, μg/kg (4M) | 23/256 | 1.01 (1.00–1.04) | 0.19 | 20/256 | 0.95 (0.85–1.03) | 0.32 | 16/256 | 0.89 (0.76–1.00) | 0.10 |
| Infant urine, μg/L (4M) | 25/266 | 0.99 (0.93–1.04) | 0.85 | 21/266 | 1.00 (0.93–1.05) | 0.91 | 23/266 | 0.99 (0.93–1.04) | 0.82 |
| ADJUSTED3 | |||||||||
| Dietary intake, μg/d (GW34) | 38/368 | 0.94 (0.88–1.01) | 0.10 | 32/368 | 1.00 (0.93–1.06) | 0.89 | 31/368 | 0.95 (0.87–1.02) | 0.15 |
| Maternal urine, μg/L (GW29) | 38/378 | 1.03 (0.99–1.06) | 0.11 | 33/378 | 1.03 (0.99–1.07) | 0.09 | 33/378 | 0.96 (0.90–1.01) | 0.17 |
| Dietary intake, μg/d (4M) | 37/372 | 0.94 (0.87–1.00) | 0.07 | 31/372 | 0.99 (0.92–1.05) | 0.71 | 31/372 | 0.90 (0.82–0.97) | 0.01 |
| Breast milk, μg/kg (4M) | 23/256 | 1.01 (1.00–1.06) | 0.17 | 20/256 | 0.96 (0.86–1.04) | 0.39 | 16/256 | 0.89 (0.76–1.00) | 0.11 |
| Infant urine, μg/L (4M) | 25/265 | 1.00 (0.93–1.05) | 0.90 | 21/265 | 1.00 (0.93–1.06) | 0.98 | 22/265 | 0.98 (0.91–1.04) | 0.63 |
Concentrations were included in the models as continuous explanatory variables and the odds ratios are calculated for an increase of 10 μg.
Number of children with allergy diagnosis.
Number of children without allergy diagnosis.
All models were adjusted for the covariates: allergic heredity (yes/no), older sibling (yes/no) and season of birth (dark/bright).