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. 2021 Dec 17;8:733602. doi: 10.3389/fnut.2021.733602

Table 5.

Logistic regression analyses of iodine status with infant allergy diagnosis at 12 months of age.

Biomarker or intake per 10 μg n Food allergy OR (95% CI) p n Atopic eczema OR (95% CI) p n Asthma OR (95% CI) p
UNADJUSTED
Dietary intake, μg/d (GW34) 381/3702 0.94 (0.88–1.01) 0.11 32/370 1.00 (0.93–1.06) 0.89 32/370 0.96 (0.88–1.02) 0.22
Maternal urine, μg/L (GW29) 38/380 1.03 (0.99–1.06) 0.10 33/380 1.03 (0.99–1.07) 0.07 34/380 0.95 (0.89–1.01) 0.12
Dietary intake, μg/d (4M) 37/373 0.94 (0.87–1.00) 0.07 31/373 0.99 (0.92–1.05) 0.68 32/373 0.91 (0.83–0.98) 0.02
Breast milk, μg/kg (4M) 23/256 1.01 (1.00–1.04) 0.19 20/256 0.95 (0.85–1.03) 0.32 16/256 0.89 (0.76–1.00) 0.10
Infant urine, μg/L (4M) 25/266 0.99 (0.93–1.04) 0.85 21/266 1.00 (0.93–1.05) 0.91 23/266 0.99 (0.93–1.04) 0.82
ADJUSTED3
Dietary intake, μg/d (GW34) 38/368 0.94 (0.88–1.01) 0.10 32/368 1.00 (0.93–1.06) 0.89 31/368 0.95 (0.87–1.02) 0.15
Maternal urine, μg/L (GW29) 38/378 1.03 (0.99–1.06) 0.11 33/378 1.03 (0.99–1.07) 0.09 33/378 0.96 (0.90–1.01) 0.17
Dietary intake, μg/d (4M) 37/372 0.94 (0.87–1.00) 0.07 31/372 0.99 (0.92–1.05) 0.71 31/372 0.90 (0.82–0.97) 0.01
Breast milk, μg/kg (4M) 23/256 1.01 (1.00–1.06) 0.17 20/256 0.96 (0.86–1.04) 0.39 16/256 0.89 (0.76–1.00) 0.11
Infant urine, μg/L (4M) 25/265 1.00 (0.93–1.05) 0.90 21/265 1.00 (0.93–1.06) 0.98 22/265 0.98 (0.91–1.04) 0.63

Concentrations were included in the models as continuous explanatory variables and the odds ratios are calculated for an increase of 10 μg.

1

Number of children with allergy diagnosis.

2

Number of children without allergy diagnosis.

3

All models were adjusted for the covariates: allergic heredity (yes/no), older sibling (yes/no) and season of birth (dark/bright).