Table 6.
Logistic regression analyses of selenium status with infant allergy diagnosis at 12 months of age.
| Biomarker or intake per 10 μg | n | Food allergy OR (95% CI) | p | n | Atopic eczema OR (95% CI) | p | n | Asthma OR (95% CI) | p |
|---|---|---|---|---|---|---|---|---|---|
| UNADJUSTED | |||||||||
| Dietary intake, μg/d (GW34) | 381/3702 | 0.90 (0.74–1.08) | 0.30 | 32/370 | 0.89 (0.71–1.08) | 0.28 | 32/370 | 1.04 (0.87–1.21) | 0.67 |
| Maternal plasma, μg/kg (GW29) | 39/380 | 1.16 (0.92–1.46) | 0.19 | 33/380 | 1.08 (0.84–1.38) | 0.53 | 34/380 | 1.10 (0.85–1.40) | 0.47 |
| Maternal erythrocytes, μg/kg (GW29) | 40/379 | 0.98 (0.84–1.13) | 0.74 | 34/379 | 0.98 (0.84–1.15) | 0.85 | 34/379 | 1.00 (0.85–1.17) | 1.00 |
| Dietary intake, μg/d (4M) | 37/373 | 0.95 (0.78–1–11) | 0.54 | 31/373 | 1.03 (0.86–1.21) | 0.73 | 32/373 | 0.90 (0.72–1.08) | 0.30 |
| Breast milk, μg/kg (4M) | 23/256 | 1.00 (0.83–1.15) | 0.99 | 20/256 | 0.95 (0.76–1.12) | 0.61 | 16/256 | 1.07 (0.90–1.22) | 0.35 |
| Infant erythrocytes, μg/kg (4M) | 18/166 | 0.83 (0.62–1.10) | 0.22 | 18/166 | 0.86 (0.64–1.13) | 0.28 | 8/166 | 1.22 (0.83–1.76) | 0.30 |
| ADJUSTED3 | |||||||||
| Dietary intake, μg/d (GW34) | 38/368 | 0.90 (0.73–1.07) | 0.27 | 32/368 | 0.88 (0.70–1.08) | 0.26 | 31/368 | 1.02 (0.84–1.20) | 0.84 |
| Maternal plasma, μg/kg (GW29) | 39/378 | 1.19 (0.94–1.49) | 0.14 | 33/378 | 1.12 (0.87–1.43) | 0.37 | 33/378 | 1.11 (0.86–1.43) | 0.40 |
| Maternal erythrocytes, μg/kg (GW29) | 40/377 | 0.99 (0.84–1.15) | 0.88 | 34/377 | 1.01 (0.85–1.19) | 0.88 | 33/377 | 1.00 (0.83–1.18) | 0.96 |
| Dietary intake, μg/d (4M) | 37/372 | 0.96 (0.79–1.12) | 0.62 | 31/372 | 1.04 (0.86–1.22) | 0.67 | 31/372 | 0.87 (0.69–1.06) | 0.21 |
| Breast milk, μg/kg (4M) | 23/256 | 1.01 (0.83–1.17) | 0.95 | 20/256 | 0.95 (0.76–1.15) | 0.64 | 16/256 | 1.07 (0.88–1.23) | 0.41 |
| Infant erythrocytes, μg/kg (4M) | 18/165 | 0.89 (0.65–1.17) | 0.42 | 18/165 | 1.03 (0.76–1.38) | 0.86 | 8/165 | 1.22 (0.84–1.78) | 0.29 |
Concentrations were included in the models as continuous explanatory variables and the odds ratios are calculated for an increase of 10 μg, with the exception for concentrations in breast milk which were investigated per μg.
1
Number of children with allergy diagnosis.
2
Number of children without allergy diagnosis.
3
All models were adjusted for the covariates: allergic heredity (yes/no), older sibling (yes/no) and season of birth (dark/bright).